Ebola Virus Net is the web resource for anyone interested in ebola. Ebola (Ebola hemorrhagic fever), is a severe, often fatal disease in humans and nonhuman primates such as monkeys, gorillas, and chimpanzees. Ebola is a rare and deadly disease caused by infection with a virus of the family Filoviridae, genus Ebolavirus. There are five identified Ebolavirus species, four of which have caused disease in humans. Ebola is found in several African countries. The first Ebola species was discovered in 1976 near the Ebola River in the Democratic Republic of the Congo. Since then, outbreaks have appeared sporadically in Africa. The largest outbreak to date was the epidemic in West Africa, which occurred from December 2013, to January 2016, with 28,646 cases and 11,323 deaths. Other outbreaks in Africa began in the Democratic Republic of the Congo in May 2017 and 2018. In July 2019, the World Health Organization declared the Congo Ebola outbreak a world health emergency.
When an infection does occur in humans, the virus can be spread to others through direct contact with the blood or body fluids of a person who is sick with Ebola, or through contact with objects that have been contaminated with the blood or body fluids of an infected person. Until recent, no vaccines were effective. In December 2016, Ebola was found to be 70–100% prevented by rVSV-ZEBOV vaccine, making it the first proven vaccine against the disease. More than 100,000 people have been vaccinated against Ebola as of 2019.
The objectives of Ebola Virus Net are to be the public and professional information resource for ebola and to serve as a network in the exchange of information and news related to ebola.
- Ebola Virus Disease –Democratic Republic of the Congo - World Health Organization
Thu, 29 Sep 2022 17:23 GMT
- Scientists race to test vaccines for Uganda's Ebola outbreak - Science
Thu, 29 Sep 2022 17:15 GMT
- Uganda Fights Deadly Ebola Outbreak as President Assures It's Under Control - Voice of America - VOA News
Thu, 29 Sep 2022 12:07 GMT
- Rare Ebola outbreak declared in Uganda | | 1UN News - UN News
Tue, 20 Sep 2022 07:00 GMT
- Structure of the Ebola virus polymerase complex - Nature.com
Wed, 28 Sep 2022 15:27 GMT
- 5 steps to stop Ebola spreading in East Africa – a frontline expert advises - The Conversation
Thu, 29 Sep 2022 14:13 GMT
- Reps raise the alarm over possible Ebola outbreak - Punch Newspapers
Fri, 30 Sep 2022 01:22 GMT
- How Uganda plans to contain a new Ebola outbreak - The Indian Express
Fri, 30 Sep 2022 04:21 GMT
- OraSure receives $8.6M to develop next-gen Ebola test - Mass Device
Wed, 28 Sep 2022 13:12 GMT
- Ebola: New WHO Treatment Recommendations - Medscape
Wed, 14 Sep 2022 07:00 GMT
- DR Congo: Ebola Outbreak - Aug 2022 - ReliefWeb
Wed, 14 Sep 2022 07:12 GMT
- Uganda's Ebola outbreak: Why is it so serious? - Yahoo! Voices
Fri, 30 Sep 2022 00:25 GMT
- Outbreak of Rare Ebola Strain Declared in Uganda - The Wall Street Journal
Tue, 20 Sep 2022 07:00 GMT
- Ebola survivors to forego sex for 90 days - The East African
Thu, 29 Sep 2022 13:14 GMT
- Ebola outbreak could be predicted based on individual risk factor data, research shows - News-Medical.Net
Thu, 01 Sep 2022 07:00 GMT
- PRO/AH/EDR> Ebola update (44): Burkina Faso ex Cote d'Ivoire, 2nd case, NOT
Mon, 30 Aug 2021 11:01:25 -0400
Ebola -- Burkina Faso
On 22 Aug 2021, the Ministry of Health informed the population of the admission to the Medical Emergencies of the Bogodogo University Hospital (CHU-B) of a 22-year-old patient who had stayed in the Republic of [Cote d'Ivoire]. The diagnostic procedure consisted of sampling analysis at the National Reference Laboratory for Viral Haemorrhagic Fever (LNR-FHV at the Muraz Centre) and the Pasteur Institute of Dakar for confirmation. The results obtained make it possible to permanently rule out
- Identification of promising anti-EBOV inhibitors: de novo drug design, molecular docking and molecular dynamics studies Fri, 30 Sep 2022 06:00:00 -0400
The Ebola virus (EBOV) outbreak was recorded as the largest in history and caused many fatalities. As seen in previous studies, drug repurposing and database filtration were the two major pathways to searching for potent compounds against EBOV. In this study, a deep learning (DL) approach via the LigDream tool was employed to obtain novel and effective anti-EBOV inhibitors. Based on the galidesivir (BCX4430) chemical structure, 100 compounds were collected and inspected using various in silico...
- Structure of the Ebola virus polymerase complex Wed, 28 Sep 2022 06:00:00 -0400
Filoviruses, including Ebola virus, pose an increasing threat to the public health. Although two therapeutic monoclonal antibodies have been approved to treat the Ebola virus disease^(1,2), there are no approved broadly reactive drugs to control diverse filovirus infection. Filovirus has a large polymerase (L) protein and the cofactor viral protein 35 (VP35), which constitute the basic functional unit responsible for virus genome RNA synthesis³. Owing to its conservation, the L-VP35 polymerase...
- Human preparedness: Relational infrastructures and medical countermeasures in Sierra Leone Wed, 28 Sep 2022 06:00:00 -0400
This paper examines health worker experiences in two areas of post-epidemic preparedness in Sierra Leone - vaccine trials and laboratory strengthening - to reflect on the place of people in current models of epidemic response. Drawing on ethnographic research and interviews with health workers in the aftermath of Ebola, it explores the hopes and expectations that interventions foster for frontline workers in under-resourced health systems, and describes the unseen work involved in sustaining...
- Investigation of and Strategies to Control the Final Cluster of the 2018-2020 Ebola Virus Disease Outbreak in the Eastern Democratic Republic of Congo Wed, 28 Sep 2022 06:00:00 -0400
CONCLUSIONS: This study illustrates the high risk of additional flare-ups in the period leading to the end-of-outbreak declaration and the importance of maintaining enhanced surveillance and confinement activities to rapidly control Ebola outbreaks.
- Social media: A new tool for outbreak surveillance Wed, 28 Sep 2022 06:00:00 -0400
Social media platforms allow users to share news, ideas, thoughts, and opinions on a global scale. Data processing methods allow researchers to automate the collection and interpretation of social media posts for efficient and valuable disease surveillance. Data derived from social media and internet search trends have been used successfully for monitoring and forecasting disease outbreaks such as Zika, Dengue, MERS, and Ebola viruses. More recently, data derived from social media have been used...
- Hydrophobic diversification is the key to simultaneously increased antifungal activity and decreased cytotoxicity of two ab initio designed peptides Tue, 27 Sep 2022 06:00:00 -0400
The fact that some antimicrobial peptides have been utilized clinically and as food preservatives stimulated the efforts in search of new candidates. In our previous studies, we succeeded in designing potent peptides against methicillin-resistant Staphylococcus aureus (MRSA), severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2), and Ebola viruses based on the database filtering technology. The designed peptides were proved highly potent. However, this ab initio method has not been...
- The PA profession in Liberia: A case study in pioneering innovation and resiliency Tue, 27 Sep 2022 06:00:00 -0400
In Liberia, the physician assistant (PA) profession began in the mid-1960s. PAs have had a major role in providing access to healthcare for patients, many of whom live in poverty and reside in remote areas where access to physicians may be severely limited. In 1964, representatives from UNICEF selected Agnes N. Dagbe, MS, RN, to be the first director of a new PA program to be developed at the Tubman National Institute of Medical Arts. Dagbe was sent to Russia to learn about their feldsher...
- Understanding Experience of Patients With Highly Infectious Diseases During Extended Isolation: A Design Perspective Tue, 27 Sep 2022 06:00:00 -0400
CONCLUSIONS: The isolation can take a toll on physiological and psychological well-being. A thoughtful design of isolation units may improve patients' experience by supporting human and social interactions, empowering patients through space flexibility and personalization of space, and supporting a more holistic approach to isolation care.
- Influence of epidemics and pandemics on paediatric ED use: a systematic review Mon, 26 Sep 2022 06:00:00 -0400
CONCLUSIONS: The scale and direction of effect of PED use depend on both the epidemic disease, the public health measures enforced and how these influence decision-making. Policy makers must be aware how fear of virus among the general public may influence their response to public health advice. There is large inequity in reporting of epidemic impact on PED use which needs to be addressed.
- The Diagnostic Accuracy of Rapid Diagnostic Tests for Ebola Virus Disease: a Systematic Review Mon, 26 Sep 2022 06:00:00 -0400
CONCLUSIONS: RDTs possess both a high sensitivity and specificity compared to RT-PCR amongst symptomatic patients presenting to Ebola Treatment Units. Our findings support the use of RDTs as a 'rule in' test to expedite treatment and vaccination.