Ebola Virus Net is the web resource for anyone interested in ebola. Ebola (Ebola hemorrhagic fever), is a severe, often fatal disease in humans and nonhuman primates such as monkeys, gorillas, and chimpanzees. Ebola is a rare and deadly disease caused by infection with a virus of the family Filoviridae, genus Ebolavirus. There are five identified Ebolavirus species, four of which have caused disease in humans. Ebola is found in several African countries. The first Ebola species was discovered in 1976 near the Ebola River in the Democratic Republic of the Congo. Since then, outbreaks have appeared sporadically in Africa. The largest outbreak to date was the epidemic in West Africa, which occurred from December 2013, to January 2016, with 28,646 cases and 11,323 deaths. Other outbreaks in Africa began in the Democratic Republic of the Congo in May 2017 and 2018. In July 2019, the World Health Organization declared the Congo Ebola outbreak a world health emergency.

When an infection does occur in humans, the virus can be spread to others through direct contact with the blood or body fluids of a person who is sick with Ebola, or through contact with objects that have been contaminated with the blood or body fluids of an infected person. Until recent, no vaccines were effective. In December 2016, Ebola was found to be 70–100% prevented by rVSV-ZEBOV vaccine, making it the first proven vaccine against the disease. More than 100,000 people have been vaccinated against Ebola as of 2019.

The objectives of Ebola Virus Net are to be the public and professional information resource for ebola and to serve as a network in the exchange of information and news related to ebola.

• West Africa steps up efforts to tackle latest Ebola threat - UN News
  Thu, 25 Feb 2021 19:31 GMT
• WHO | Ebola virus disease – Guinea - WHO/Europe
  Wed, 17 Feb 2021 08:00 GMT
• Ebola Expert Calls for Vigilance Amid Outbreaks - Voice of America
  Tue, 23 Feb 2021 01:42 GMT
• Véronique Tadjo's 'In The Company Of Men' Focuses On West Africa's Ebola Outbreak - NPR
  Wed, 24 Feb 2021 21:57 GMT
• MSF moves to support community affected by Ebola in North Kivu, Democratic Republic of Congo - Democratic Republic of the Congo - ReliefWeb
  Thu, 25 Feb 2021 19:42 GMT
• Guinea Declares Ebola Outbreak - NPR
  Sun, 14 Feb 2021 08:00 GMT
• Ebola virus disease – Democratic Republic of the Congo - WHO/Europe
  Wed, 10 Feb 2021 08:00 GMT
• West African countries ramp up Ebola preparedness - Guinea - ReliefWeb
  Thu, 25 Feb 2021 18:22 GMT
• Multiple Countries | Ebola Virus Disease (EVD) Outbreak: Preparedness and Response - Emergency Appeal: n° MDREBOLA21 (19 February 2021) - Guinea - ReliefWeb
  Sat, 20 Feb 2021 18:44 GMT
• Disease outbreak news: Ebola virus disease – Guinea (17 February 2021) - Guinea - ReliefWeb
  Thu, 18 Feb 2021 03:50 GMT
• Ebola: 20,000 vaccine doses to tackle Guinea outbreak - SciDev.Net
  Thu, 25 Feb 2021 14:56 GMT
• New Ebola Outbreak Threatens in Congo - The New York Times
  Tue, 09 Feb 2021 08:00 GMT
• Women's groups lead fight against misinformation as Ebola returns to DRC - Democratic Republic of the Congo - ReliefWeb
  Wed, 24 Feb 2021 11:52 GMT
• UNICEF DRC Ebola Situation Report No. 3: 15 - 19 February 2021 - Democratic Republic of the Congo - ReliefWeb
  Fri, 19 Feb 2021 08:00 GMT
• Republic of Guinea - Ebola Virus Disease outbreak (Emergency Response Coordination Centre (ERCC) – DG ECHO Daily Map | 24/02/2021 - Guinea - ReliefWeb
  Wed, 24 Feb 2021 16:48 GMT

• PRO/AH/EDR> Ebola update (19): Guinea (NZ), Congo DR (NK)
  Thu, 25 Feb 2021 13:17:49 -0500
  Ebola -- DR Congo
  The 1st priority must be to make the response relevant to each context. Previous Humanitarian Policy Group (HPG) research on the 2014-2016 outbreak in West Africa and forthcoming research on the 2018-2020 outbreak in the DRC (commonly known as DRC's 10th outbreak) demonstrates that the main challenge at the outset is to place context at the centre of understanding problems and charting a strategy forward. We know from previous responses that this cannot be reduced to an anthropological

• A community's experience during and after the Ebola epidemic of 2014-2016 in Sierra Leone: A qualitative study Thu, 25 Feb 2021 06:00:00 -0500
  CONCLUSIONS: The findings of this qualitative study reveal that the Ebola epidemic was a traumatizing period for the Calaba Town community, and that confusion and distrust toward the government health care system have continued. Future studies should explore the extended impact of the epidemic on communities, including long-term psychological, social, and economic consequences of this outbreak.
• New Vaccine-Manufacturing Methods Are Moving Away From the Egg Thu, 25 Feb 2021 06:00:00 -0500
  With seasonal influenza, Ebola, shingles, pneumonia, human papillomavirus, and other pathogens-combined now with the novel coronavirus (SARS-CoV-2)-the world's demand for vaccines is on a steep incline. New vaccine development is progressing rapidly, as seen with recent announcements of coronavirus options [1], [2], but what about their manufacture?
• Crystal structure of human LC8 bound to a peptide from Ebola virus VP35 Thu, 25 Feb 2021 06:00:00 -0500
  Zaire ebolavirus, commonly called Ebola virus (EBOV), is an RNA virus that causes severe hemorrhagic fever with high mortality. Viral protein 35 (VP35) is a virulence factor encoded in the EBOV genome. VP35 inhibits host innate immune responses and functions as a critical cofactor for viral RNA replication. EBOV VP35 contains a short conserved motif that interacts with dynein light chain 8 (LC8), which serves as a regulatory hub protein by associating with various LC8-binding proteins. Herein,...
• What community-based public health approaches in West Africa for COVID-19 epidemic? A reflection based on the African socio-cultural context Wed, 24 Feb 2021 06:00:00 -0500
  The social and cultural dimensions of health influence the course of disease and condition the success of health interventions. In Africa, previous epidemics such as Ebola have shown the importance of contextualizing health interventions. This literature review contributes to the reflection on the analysis of community-based interventions in the context of the particularities of West Africa in the fight against the pandemic in COVID-19.
• COVID-19 pandemic, Uganda's story Wed, 24 Feb 2021 06:00:00 -0500
  As the COVID-19 pandemic continues to ravage health care systems, economies, livelihoods, and cultures across the world, responses across countries have varied greatly. Uganda adopted its own model taking into consideration its culture, values, environment, socio-economic activities, beliefs, previous successful epidemic experience, and appears a hybrid policy to the Norwegian model. This model of response is perhaps based on Uganda's long experience in successful control of many previous...
• Biological activity-based modeling identifies antiviral leads against SARS-CoV-2 Wed, 24 Feb 2021 06:00:00 -0500
  Computational approaches for drug discovery, such as quantitative structure-activity relationship, rely on structural similarities of small molecules to infer biological activity but are often limited to identifying new drug candidates in the chemical spaces close to known ligands. Here we report a biological activity-based modeling (BABM) approach, in which compound activity profiles established across multiple assays are used as signatures to predict compound activity in other assays or...
• Identifying Potentially Beneficial Genetic Mutations Associated with Monophyletic Selective Sweep and a Proof-of-Concept Study with Viral Genetic Data Wed, 24 Feb 2021 06:00:00 -0500
  Genetic mutations play a central role in evolution. For a significantly beneficial mutation, a one-time mutation event suffices for the species to prosper and predominate through the process called "monophyletic selective sweep." However, existing methods that rely on counting the number of mutation events to detect selection are unable to find such a mutation in selective sweep. We here introduce a method to detect mutations at the single amino acid/nucleotide level that could be responsible...
• Understanding the long-term evolution and predictors of sequelae of Ebola virus disease survivors in Guinea: A 48-month prospective, longitudinal cohort study (PostEboGui) Tue, 23 Feb 2021 06:00:00 -0500
  CONCLUSION: Our findings provide new insight into the long-term clinical complications of EVD and their significant association with symptoms in the acute phase, thus reinforcing the importance of regular, long-term follow-up for EVD survivors.
• Epidemiology of Viral Induced Anterior Uveitis Mon, 22 Feb 2021 06:00:00 -0500
  Purpose: Viral agents are the most common cause of infectious anterior uveitis worldwide. The purpose of this review is to analyze the frequency, gender and racial differences of viral anterior uveitis (VAU) in various populations. Methods: Systematized literature review of epidemiological reports of VAU cited in PubMed, EMBASE and the Cochrane Library database published until June 30th, 2020. Results: A total of 12 clinical studies on epidemiology of definite VAU and 36 clinical studies of...
• Modeling and tracking Covid-19 cases using Big Data analytics on HPCC system platformm Mon, 22 Feb 2021 06:00:00 -0500
  This project is funded by the US National Science Foundation (NSF) through their NSF RAPID program under the title "Modeling Corona Spread Using Big Data Analytics." The project is a joint effort between the Department of Computer & Electrical Engineering and Computer Science at FAU and a research group from LexisNexis Risk Solutions. The novel coronavirus Covid-19 originated in China in early December 2019 and has rapidly spread to many countries around the globe, with the number of confirmed...