Ebola Virus Net is the web resource for anyone interested in ebola. Ebola (Ebola hemorrhagic fever), is a severe, often fatal disease in humans and nonhuman primates such as monkeys, gorillas, and chimpanzees. Ebola is a rare and deadly disease caused by infection with a virus of the family Filoviridae, genus Ebolavirus. There are five identified Ebolavirus species, four of which have caused disease in humans. Ebola is found in several African countries. The first Ebola species was discovered in 1976 near the Ebola River in the Democratic Republic of the Congo. Since then, outbreaks have appeared sporadically in Africa. The largest outbreak to date was the epidemic in West Africa, which occurred from December 2013, to January 2016, with 28,646 cases and 11,323 deaths. Other outbreaks in Africa began in the Democratic Republic of the Congo in May 2017 and 2018. In July 2019, the World Health Organization declared the Congo Ebola outbreak a world health emergency.
When an infection does occur in humans, the virus can be spread to others through direct contact with the blood or body fluids of a person who is sick with Ebola, or through contact with objects that have been contaminated with the blood or body fluids of an infected person. Until recent, no vaccines were effective. In December 2016, Ebola was found to be 70–100% prevented by rVSV-ZEBOV vaccine, making it the first proven vaccine against the disease. More than 100,000 people have been vaccinated against Ebola as of 2019.
The objectives of Ebola Virus Net are to be the public and professional information resource for ebola and to serve as a network in the exchange of information and news related to ebola.
- U.S. lifting Ebola travel restrictions on Guinea - Reuters
Thu, 13 May 2021 21:23 GMT
- Ebola Virus Disease (EVD) - Regional Emergency Health Response Plan 2020-2022 (updated: 27 April 2021) - Democratic Republic of the Congo - ReliefWeb
Tue, 27 Apr 2021 07:00 GMT
- Johnson & Johnson Joins World Health Organization in Efforts to Prevent Spread of Ebola in West Africa - PRNewswire
Thu, 13 May 2021 12:00 GMT
- Latest deadly Ebola virus outbreak in DR Congo declared over - UN News
Mon, 03 May 2021 07:00 GMT
- Outbreak Brief 10: Ebola virus disease (EVD) Outbreak – Africa CDC - africacdc.org
Tue, 27 Apr 2021 07:00 GMT
- Democratic Republic of the Congo (DRC), Africa: Ebola Virus Disease outbreak (MDRCD026), Operations Update n° 9 - Democratic Republic of the Congo - ReliefWeb
Sat, 08 May 2021 03:54 GMT
- Spillover or endemic? Reconsidering the origins of Ebola virus disease outbreaks by revisiting local accounts in light of new evidence from Guinea - Guinea - ReliefWeb
Sat, 24 Apr 2021 07:00 GMT
- Fear and stigma remain in survivors of Africa's Ebola epidemic - The BMJ
Mon, 10 May 2021 09:26 GMT
- New Tech Makes Detecting Airborne Ebola Virus Possible - Newswise
Tue, 20 Apr 2021 07:00 GMT
- Outbreak Brief 9: Ebola virus disease (EVD) Outbreak – Africa CDC - africacdc.org
Tue, 20 Apr 2021 07:00 GMT
- Scientists unveil new Ebola virus vaccine design - News-Medical.Net
Thu, 13 May 2021 04:38 GMT
- New vaccine design developed to protect against Ebola virus - Drug Target Review
Thu, 13 May 2021 10:47 GMT
- Ebola Outbreak in DRC Declared Over - Contagionlive.com - Contagionlive.com
Mon, 10 May 2021 19:16 GMT
- An unprecedented genomic analysis helped to curb an Ebola outbreak - Nature.com
Thu, 15 Apr 2021 07:00 GMT
- New accusations of sexual abuse in DR Congo's Ebola drive - FRANCE 24
Wed, 12 May 2021 12:14 GMT
- PRO/AH/EDR> Ebola update (34): DR Congo (NK) outbreak end, research
Tue, 04 May 2021 05:34:43 -0400
Ebola -- DR Congo
The Democratic Republic of Congo on Mon 3 May 2021 declared the end of an Ebola outbreak that infected 12 people in the eastern province of North Kivu and killed 6 of them. The outbreak was contained using Merck's (MRK.N) Ebola vaccine, which was given to more than 1600 of the patients' contacts and contacts of contacts, the aid group Medecins Sans Frontieres (MSF), said.
The cases were genetically linked to the 2018-20 Ebola epidemic that killed more than 2200 people, the second highest
- Colonial Virus": COVID-19, creative arts and public health communication in Ghana Wed, 12 May 2021 06:00:00 -0400
Since March 2020, Ghana's creative arts communities have tracked the complex facets of the COVID-19 pandemic through various art forms. This paper reports a study that analysed selected 'COVID art forms' through arts and health and critical health psychology frameworks. Art forms produced between March and July 2020, and available in the public sphere - traditional media, social media and public spaces - were collated. The data consisted of comedy, cartoons, songs, murals and textile designs....
- Single-component multilayered self-assembling nanoparticles presenting rationally designed glycoprotein trimers as Ebola virus vaccines Wed, 12 May 2021 06:00:00 -0400
Ebola virus (EBOV) glycoprotein (GP) can be recognized by neutralizing antibodies (NAbs) and is the main target for vaccine design. Here, we first investigate the contribution of the stalk and heptad repeat 1-C (HR1(C)) regions to GP metastability. Specific stalk and HR1(C) modifications in a mucin-deleted form (GPΔmuc) increase trimer yield, whereas alterations of HR1(C) exert a more complex effect on thermostability. Crystal structures are determined to validate two rationally designed GPΔmuc...
- Highly Sensitive Point-of-Care Ebola Diagnostic In Development Tue, 11 May 2021 06:00:00 -0400
- Fear and stigma remain in survivors of Africa's Ebola epidemic Tue, 11 May 2021 06:00:00 -0400
- Dual-axis Volta phase plate cryo-electron tomography of Ebola virus-like particles reveals actin-VP40 interactions Mon, 10 May 2021 06:00:00 -0400
Cryo-electron tomography (cryo-ET) is a pivotal imaging technique for studying the structure of pleomorphic enveloped viruses and their interactions with the host at native conditions. Owing to the limited tilting range of samples with a slab geometry, electron tomograms suffer from so-called missing wedge information in Fourier space. In dual-axis cryo-ET, two tomograms reconstructed from orthogonally oriented tilt series are combined into a tomogram with improved resolution as the missing...
- A multi-stage stochastic programming approach to epidemic resource allocation with equity considerations Mon, 10 May 2021 06:00:00 -0400
Existing compartmental models in epidemiology are limited in terms of optimizing the resource allocation to control an epidemic outbreak under disease growth uncertainty. In this study, we address this core limitation by presenting a multi-stage stochastic programming compartmental model, which integrates the uncertain disease progression and resource allocation to control an infectious disease outbreak. The proposed multi-stage stochastic program involves various disease growth scenarios and...
- Understanding misinformation infodemic during public health emergencies due to large-scale disease outbreaks: a rapid review Mon, 10 May 2021 06:00:00 -0400
CONCLUSION: This review identified the nature and pattern of misinformation during large-scale infectious disease outbreaks, which could potentially be used to address misinformation during the ongoing COVID-19 or any future pandemic.
- Building the Sierra Leone Ebola Database: organization and characteristics of data systematically collected during 2014-2015 Ebola epidemic Sun, 09 May 2021 06:00:00 -0400
BACKGROUND: During the 2014-2016 Ebola outbreak in West Africa, the Sierra Leone Ministry of Health and Sanitation (MoHS), the US Centers for Disease Control and Prevention, and responding partners under the coordination of the National Ebola Response Center (NERC) and the MoHS's Emergency Operation Center (EOC) systematically recorded information from the 117 Call Center system and district alert phone lines, case investigations, laboratory sample testing, clinical management, and safe and...
- The methyltransferase domain of the Respiratory Syncytial Virus L protein catalyzes cap N7 and 2'-O-methylation Thu, 06 May 2021 06:00:00 -0400
Respiratory syncytial virus (RSV) is a negative sense single-stranded RNA virus and one of the main causes of severe lower respiratory tract infections in infants and young children. RSV RNA replication/transcription and capping are ensured by the viral Large (L) protein. The L protein contains a polymerase domain associated with a polyribonucleotidyl transferase domain in its N-terminus, and a methyltransferase (MTase) domain followed by the C-terminal domain (CTD) enriched in basic amino acids...
- African based researchers' output on models for the transmission dynamics of infectious diseases and public health interventions: A scoping review Thu, 06 May 2021 06:00:00 -0400
CONCLUSIONS: Research productivity in applied epidemiological modelling studies of infectious diseases may have increased, but there remains an under-representation of African researchers as leading authors. The study findings indicate a need for the development of research capacity through supporting existing institutions in Africa and promoting research funding that will address local health priorities.