Ebola Virus Net is the web resource for anyone interested in ebola. Ebola (Ebola hemorrhagic fever), is a severe, often fatal disease in humans and nonhuman primates such as monkeys, gorillas, and chimpanzees. Ebola is a rare and deadly disease caused by infection with a virus of the family Filoviridae, genus Ebolavirus. There are five identified Ebolavirus species, four of which have caused disease in humans. Ebola is found in several African countries. The first Ebola species was discovered in 1976 near the Ebola River in the Democratic Republic of the Congo. Since then, outbreaks have appeared sporadically in Africa. The largest outbreak to date was the epidemic in West Africa, which occurred from December 2013, to January 2016, with 28,646 cases and 11,323 deaths. Other outbreaks in Africa began in the Democratic Republic of the Congo in May 2017 and 2018. In July 2019, the World Health Organization declared the Congo Ebola outbreak a world health emergency.

When an infection does occur in humans, the virus can be spread to others through direct contact with the blood or body fluids of a person who is sick with Ebola, or through contact with objects that have been contaminated with the blood or body fluids of an infected person. Until recent, no vaccines were effective. In December 2016, Ebola was found to be 70–100% prevented by rVSV-ZEBOV vaccine, making it the first proven vaccine against the disease. More than 100,000 people have been vaccinated against Ebola as of 2019.

The objectives of Ebola Virus Net are to be the public and professional information resource for ebola and to serve as a network in the exchange of information and news related to ebola.

• Tanzania confirms first-ever outbreak of Marburg Virus Disease - WHO | Regional Office for Africa
  Tue, 21 Mar 2023 12:00 GMT
• Tanzanian officials confirm 5 dead from Marburg disease - The Seattle Times
  Tue, 21 Mar 2023 19:35 GMT
• Tanzania says five dead in Marburg virus outbreak - Al Arabiya English
  Tue, 21 Mar 2023 17:32 GMT
• Tanzania says five dead in Marburg virus outbreak - News24
  Tue, 21 Mar 2023 18:44 GMT
• Tanzania declares outbreak of Ebola-like Marburg virus - BNO News
  Tue, 21 Mar 2023 19:32 GMT
• Unidentified Illness Kills Five in Tanzania, Sparks Ebola Fears - Voice of America - VOA News
  Fri, 17 Mar 2023 17:17 GMT
• An outbreak of the deadly Marburg virus has been confirmed. Here's what you need to know - CBC News
  Fri, 17 Feb 2023 08:00 GMT
• Guinea's Ebola orphans feel abandoned - DW
  Tue, 21 Mar 2023 13:05 GMT
• Spain detects first suspected case of Ebola-like Marburg virus: Report - WION
  Sat, 25 Feb 2023 08:00 GMT
• BREAKING: Tanzania Declares Outbreak of Ebola-like Marburg Virus, at Least 5 Dead - Latest Tweet by BNO - LatestLY
  Tue, 21 Mar 2023 19:35 GMT
• Preventing Ebola: The power of proactive vaccination - Devex
  Tue, 21 Feb 2023 08:00 GMT
• Russia claims US biologists may be behind Ebola virus spread in Central Africa in 2022 - Republic World
  Fri, 10 Mar 2023 08:00 GMT
• AIM ImmunoTech Announces Late-Breaking Presentation at the ... - BioSpace
  Fri, 17 Mar 2023 04:40 GMT
• Marburg virus: Should we be worried about the Ebola-like disease ... - SBS News
  Mon, 20 Feb 2023 08:00 GMT
• The World Cannot Afford 'Pandemic Fatigue' - TIME
  Fri, 17 Mar 2023 09:00 GMT

• PRO/AH/EDR> Ebola update (44): Burkina Faso ex Cote d'Ivoire, 2nd case, NOT
  Mon, 30 Aug 2021 11:01:25 -0400
  Ebola -- Burkina Faso
  On 22 Aug 2021, the Ministry of Health informed the population of the admission to the Medical Emergencies of the Bogodogo University Hospital (CHU-B) of a 22-year-old patient who had stayed in the Republic of [Cote d'Ivoire]. The diagnostic procedure consisted of sampling analysis at the National Reference Laboratory for Viral Haemorrhagic Fever (LNR-FHV at the Muraz Centre) and the Pasteur Institute of Dakar for confirmation. The results obtained make it possible to permanently rule out

• Is there any link between Hyperphosphatemia, Hypoalbuminemia, and Hypocalcemia with Hospital Outcomes in COVID-19 Patients? Tue, 21 Mar 2023 06:00:00 -0400
  CONCLUSIONS: Poor outcomes were associated with hyperphosphatemia and hypoalbuminemia. It seems that we should evaluate the patients for derangements of phosphate, albumin, and calcium and try to treat them for all COVID-19 patients.
• Common pathways targeted by viral hemorrhagic fever viruses to infect the placenta and increase the risk of stillbirth Mon, 20 Mar 2023 06:00:00 -0400
  Viral hemorrhagic fevers (VHF) are endemic to Africa, South America and Asia and contribute to significant maternal and fetal morbidity and mortality. Viruses causing VHFs are typically zoonotic, spreading to humans through livestock, wildlife, or mosquito vectors. Some of the most lethal VHF viruses also impart a high-risk of stillbirth including ebolaviruses, Marburg virus (MARV), Lassa virus (LASV), and Rift Valley Fever Virus (RVFV). Large outbreaks and epidemics are common, though the...
• Protection, health seeking, or a laissez-passer: Participants' decision-making in an EVD vaccine trial in the eastern Democratic Republic of the Congo Sun, 19 Mar 2023 06:00:00 -0400
  During the 10th Ebola virus disease (EVD) epidemic in the eastern Democratic Republic of the Congo (DRC) (2018-2020), two experimental EVD vaccines were deployed in North Kivu. This province has been at the centre of conflict in the region for the last 25 years. Amidst ambivalence towards protracted foreign intervention and controversy about introducing two experimental vaccines, the existing literature has focused on mistrust and 'resistance' towards the Ebola response and vaccines. In this...
• Selection of phage-displayed antibodies with high affinity and specificity by electrophoresis in microfluidic devices Sat, 18 Mar 2023 06:00:00 -0400
  A method development aimed for high-throughput and automated antibody screening holds great potential for areas ranging from fundamental molecular interactions to the discovery of novel disease markers, therapeutic targets and monoclonal antibody engineering. Surface display techniques enable efficient manipulation of large molecular libraries in small volumes. Specifically, phage display appeared as a powerful technology for selecting peptides and proteins with enhanced, target-specific binding...
• Evolutionary binary feature selection using adaptive ebola optimization search algorithm for high-dimensional datasets Fri, 17 Mar 2023 06:00:00 -0400
  Feature selection problem represents the field of study that requires approximate algorithms to identify discriminative and optimally combined features. The evaluation and suitability of these selected features are often analyzed using classifiers. These features are locked with data increasingly being generated from different sources such as social media, surveillance systems, network applications, and medical records. The high dimensionality of these datasets often impairs the quality of the...
• Quantifying the value of viral genomics when inferring who infected whom in the 2014-16 Ebola virus outbreak in Guinea Fri, 17 Mar 2023 06:00:00 -0400
  Transmission trees can be established through detailed contact histories, statistical or phylogenetic inference, or a combination of methods. Each approach has its limitations, and the extent to which they succeed in revealing a 'true' transmission history remains unclear. In this study, we compared the transmission trees obtained through contact tracing investigations and various inference methods to identify the contribution and value of each approach. We studied eighty-six sequenced cases...
• Pseudotyped Viruses for Marburgvirus and Ebolavirus Wed, 15 Mar 2023 06:00:00 -0400
  Marburg virus (MARV) and Ebola virus (EBOV) of the Filoviridae family are the most lethal viruses in terms of mortality rate. However, the development of antiviral treatment is hampered by the requirement for biosafety level-4 (BSL-4) containment. The establishment of BSL-2 pseudotyped viruses can provide important tools for the study of filoviruses. This chapter summarizes general information on the filoviruses and then focuses on the construction of replication-deficient pseudotyped MARV and...
• Lessons learnt from the applying the Centers for Disease Control and Prevention (CDC) evaluation framework to the measles incident management system response, USA, 2020-2021 Tue, 14 Mar 2023 06:00:00 -0400
  The functionality and performance of public health programmes at all levels of government play a critical role in preventing, detecting, mitigating and responding to public health threats, including infectious disease outbreaks. Multiple and concurrent outbreaks in recent years, such as COVID-19, Ebola and Zika, have highlighted the importance of documenting lessons learnt from public health responses of national and global agencies. In February 2020, the US Centers for Disease Control and...
• Natural history of nonhuman primates after conjunctival exposure to Ebola virus Tue, 14 Mar 2023 06:00:00 -0400
  Transmission of Ebola virus (EBOV) primarily occurs via contact exposure of mucosal surfaces with infected body fluids. Historically, nonhuman primate (NHP) challenge studies have employed intramuscular (i.m.) or small particle aerosol exposure, which are largely lethal routes of infection, but mimic worst-case scenarios such as a needlestick or intentional release, respectively. When exposed by more likely routes of natural infection, limited NHP studies have shown delayed onset of disease and...
• Data pipelines in a public health emergency: The human in the machine Mon, 13 Mar 2023 06:00:00 -0400
  In an emergency epidemic response, data providers supply data on a best-faith effort to modellers and analysts who are typically the end user of data collected for other primary purposes such as to inform patient care. Thus, modellers who analyse secondary data have limited ability to influence what is captured. During an emergency response, models themselves are often under constant development and require both stability in their data inputs and flexibility to incorporate new inputs as novel...